Successful, multiresistant bacterial clones.

Editorial: The Global Challenge Posed by the Multiresistant International Clones of Bacterial Pathogens

Exploring Roads towards Concerted Action

withstand extreme conditions and to resist harmful drugs and other toxic agents compounds is fascinating. Use of antibacterial medicines over the last 60 years have triggered a combination of genetic and biochemical mechanisms within the bacteria to secure their survival in otherwise lethal environments. Bacterial clones with natural and acquired resistance have continuously been selected as an...

The Susceptibility Evaluation of Multiresistant Gram-Negative Bacilli to Meropenem and Imipenem

Introduction: Nosocomial infections are responsible for the much of the morbidity and mortality found in hospitals. The present study was conducted on 70 bacterial strains isolated from hospitalized patients in various medical units of Baqiyatallah Hospital in Tehran, Iran during a period of 12 months from; March to February 2009. Methods: The bacterial s...

Heteroresistance to penicillin in Streptococcus pneumoniae.

Heteroresistance to beta-lactam antibiotics has been mainly described for staphylococci, for which it complicates diagnostic procedures and therapeutic success. This study investigated whether heteroresistance to penicillin exists in Streptococcus pneumoniae. Population analysis profile (PAP) showed the presence of subpopulations with higher penicillin resistance in four of nine clinical pneumo...

Persistence of clones of coagulase-negative staphylococci among premature neonates in neonatal intensive care units: two-center study of bacterial genotyping and patient risk factors.

From 1 January 1995 until 1 January 1996, we studied the molecular epidemiology of blood isolates of coagulase-negative staphylococci (CoNS) in the Neonatal Intensive Care Units (NICUs) of the Sophia Children's Hospital (SCH; Rotterdam, The Netherlands) and the Wilhelmina Children's Hospital (WCH; Utrecht, The Netherlands). The main goal of the present study was to detect putatively endemic clo...